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Datsing BioPaper®

Biopaper ® is a new type patented bio-degradable hemostatic material. Adjunctively used in surgical procedures. It can effectively stop blood oozing in surgical wounds, prevent the tissue from adhering, and seal the surgical wound.

Product video

Product Brief

Bio-degradable Hemostatic Material (Biopaper)

A paper like membrane, made of polysaccharides, adjunctively used in surgical procedures, effectively stop blood oozing and prevent postoperative at the same time.



Excellent bio-compatibility No cytotoxicity


no skin sensitization response, no irritation, and no acute systemic toxicity


No risk for animal disease or immunogenicity


Neutral PH value.

Key features

Stop blood oozing - in surgical wounds from physical, molecular and physiological levels

Anti-adhesion - form a gel layer as physical barrier adhering to wound surface and prevent air and substance leakage

Adhesive sealing - the transparent gel layer seal the wound effectively

100% safely degraded - into CO2 and H2O within 28 days


Bio-Paper is applicable in various surgeries, such as neurosurgery, orthopedics surgery, general surgery, cardiac surgery, thoracic surgery, hepatobiliary surgery, urology to prevent the wound from blood-oozing and tissue adhesion. Besides, in the neurosurgery, the Bio-Paper can seal the dura mater to prevent the leaking of the cerebrospinal fluid.


Safety and performance information

Intended user

The device should be used only by physicians having adequate training


     1. Biopaper should not be used in patients with a known allergy to the ingredients of the product.

     2. Patients allergic to shellfish should not use the product.

     3. Biopaper should not be used to control hemorrhage from large arteries.

     4. Biopaper should not be used for controlling post-partum bleeding or menorrhagia.


Limitations of use:

The maximum amount of usage for each person is 360 cm2 (Equivalent to 9 pieces of Biopaper with the size of 5cm×8cm).


Product lifetime:

According to experiment in animals, the Bio-paper could be degraded completely within 12 weeks after application.


1.       Biopaper is provided sterile and are intended for single use. Do not resterilize. Reprocessing or re-sterilization may compromise the device integrity and could lead to patient injury, illness, or death. Reuse, even after re-sterilization, may create a risk of contamination and lead to patient infection or the transmission of infectious disease(s).

2.       Biopaper should not be re-sterilized.

3.       Use the device before the expiration date.

4.       Never leave the plastic back holder and packaging materials inside the patient’s body.

5.       Biopaper is not intended as a substitute for careful surgery and the proper use of sutures and ligatures.

6.      Biopaper must be kept dry prior to application

      7.     The surgical field, especially desired site of application, should be cleaned to remove excess fluid before the application of the device.



1.       Biopaper can be cut, folded, curled and covered to fit the wounds based on surgical needs.

2.       If the placement position need to be adjusted, please move the Biopaper within 20 seconds, or the Biopaper becomes very sticky and not easy to be moved.

3.       Foreign body reactions may occur with Biopaper, as with any implanted material.

4.       Biopaper should be handled gently with dry instruments and/or gloves, and avoid contact with tissue surfaces until directly at the site of application, especially during the endoscopic process. 

5.       In the event of re-bleeding, apply one more Biopaper to the bleeding site directly.

6.       Up to now, no hazards caused by interference between Biopaper and other equipment likely to be used in the course of other clinical procedures or medical treatments have been found.

7.       It’s no hazards to use Biopaper in MR environment and there is no effect of Biopaper on the MR image artifacts.